Pheochromocytoma symptoms pallor

Apart from the above classic presentation, pheo - chromocytoma can also present with nonspecific symptoms such as flushing, nausea, tiredness or weight loss. Abdominal pain and constipation or chest pain mimicking myocardial infarction as in the case of inverted takotsubo cardiomyopathy can be caused by sudden catecholamine releasePheochromocytomas can cause striking symptoms and signs. Hypertension is an invariable finding in patients with these tumours. It may be constant, mimicking the common forms of hypertension, or episodic and associated with headache, excessive perspiration, heart palpitation, pallor, tremour, and anxiety. Episodic attacks may end abruptly, and ... Pheochromocytoma (PCC) is a rare catecholamine-secreting neoplasm of adrenal origin; when it is extra-adrenal, it is referred to as paraganglioma. PCC is known as the "great masquerader" because of its similarity in clinical presentation to many other conditions. ... severe headache, tremors, pallor, and dyspnea. Atypical symptoms include ...Malignant metastatic pheochromocytoma should be treated with alpha-blockers and beta-blockers. The tumor may be indolent and survival long-lasting. However, even with rapid tumor growth, blood pressure can be controlled. I-131 MIBG or more recently lutetium-177 dotatate can help relieve symptoms in patients with residual disease. The symptoms mainly consist of Abdominal pain, Chest pain, Palpitations, Sweating, Increased heart rate, dry mouth, irritability, pallor, headache, Weight loss, tremors, high blood pressure, sleeping problems and increased metabolism. The symptoms may come in bouts and unpredictably and can last up to 15-20 minutes.Other possible symptoms include: Anxiety attacks Fever Irregular heartbeat Extreme paleness in the face Shortness of breath Tremors or shakiness Nausea Vomiting Clammy skin Constipation Tingling fingers Vision disturbances Chest or stomach pain Weight loss High blood sugar levels Symptom triggersAnswer (1 of 4): When can symptoms of a pheochromocytoma occur? Pheochromocytomas may occur in persons of any age, but the peak incidence is from the third to the fifth decades of life. Approximately 10% occur in children. History Symptoms and signs of pheochromocytoma include the following: ...The most common ages for symptoms of a disease to begin is called age of onset. Age of onset can vary for different diseases and may be used by a doctor to determine the diagnosis. For some diseases, symptoms may begin in a single age range or several age ranges. For other diseases, symptoms may begin any time during a person's life.These may be variable but typically include palpitation, tremor, diaphoresis, and headache. Attacks may start as a feeling of shortness of breath followed by chest pain and headache. Coldness in the hands and feet and facial pallor may occur. Spells may occur multiple times daily or as infrequently as once monthly.Pheochromocytoma. When to suspect • 5 "Ps" of paroxysm - Pressure - HTN - Pain - HA - Perspiration - profuse - Palpitation - Pallor • Diverse manifestations • Variation in hormones • Variation in sensitivities • No correlation between symptoms (even HTN) and levels • Often not consideredSymptoms and signs of pheochromocytoma include the following: Headache Diaphoresis Palpitations Tremor Nausea Weakness Pallor Anxiety, sense of doom Epigastric pain Flank pain Constipation ...Pheochromocytoma and Congestive Heart Failure. Science topic Pheochromocytoma. ... there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and ... Of interest, it is estimated that pheochromocytomas are present in 0.1-0.6% of patients with hypertension [ 13 ]. In addition to these symptoms, pallor, nausea, flushing, anxiety or a sense of doom, palpitations and abdominal pain can be part of the constellation of presenting symptoms.The clinical presentation of pheochromocytoma can vary greatly, but hypertension, tachycardia, pallor, headache and feelings of panic or anxiety are typically evident. 3,4,6 The signs and symptoms ...Pallor (face turning pale, then often followed by flushing. Tremor (shakiness). Headache. Sweating. Spells may be spontaneous or precipitated by change in body position, anxiety, medications (e.g., metoclopramide, anesthetic agents), and maneuvers that increase intraabdominal pressure (e.g. going to the bathroom).Classical symptoms are spell-like and caused by catecholamine surges, which cause episodic palpitations, headache, pallor, perspiration and anxiety. Signs are tachycardia, hypertension.Pallor, dyspnea, paresthesia, and orthostatic hypotension were the symptoms and signs which their presence increases the likelihood of pheochromocytoma; whereas diarrhea, constipation, dizziness, chest pain and tremor were the symptoms and signs which their presence decreases the likelihood of pheochromocytoma.A pheochromocytoma-induced hypertensive crisis may precipitate hypertensive encephalopathy, which is characterized by altered mental status, focal neurologic signs and symptoms, or seizures. Other neurologic complications include stroke from cerebral infarction or an embolic event secondary to a mural thrombus from dilated cardiomyopathy.What are the signs/symptoms? "Classic" triad: 1. Palpitations 2. Headache 3. Episodic diaphoresis. Also, hypertension (50%), pallor S flushing, anxiety, weight loss, tachycardia, hyperglycemia. How can the pheochromocytoma SYMPTOMS triad be remembered?A pheochromocytoma results in the irregular and excessive release of these hormones. This can lead to high blood pressure and cause symptoms such as severe headaches, irritability, sweating, rapid heart rate, nausea, vomiting, weight loss, weakness, chest pain, and anxiety.Frequency of symptoms in 100 patients with pheochromocytoma Symptom % Symptom % _____ Headache 80 Anxiety 22 Diaphoresis 71 Epigastric abdominal pain 22 Palpitation 64 Chest pain 19 Pallor 42 Dyspnoe 19 Nausea 42 Flushing 18 Tremor 31 Paresthesias or numbness 11 Generalized weakness 28 Blurring of vision 11 From JE Thomas et al., JAMA 1966, 197 ...Other possible symptoms include: Anxiety attacks Fever Irregular heartbeat Extreme paleness in the face Shortness of breath Tremors or shakiness Nausea Vomiting Clammy skin Constipation Tingling fingers Vision disturbances Chest or stomach pain Weight loss High blood sugar levels Symptom triggersPheochromocytomas, which arise from the adrenal medulla, typically lead to catecholamine excess. Symptoms of PGL/PCC result from either mass effects or catecholamine hypersecretion (e.g., sustained or paroxysmal elevations in blood pressure, headache, episodic profuse sweating, forceful palpitations, pallor, and apprehension or anxiety).What are the symptoms for pheochromocytoma diagnosis.Pediatric Considerations.Physical symptoms for pheochromocytoma diagnosis. Skip to content. Call Now ! +91-9972446882. Call Now ! +91-9972446882. Home; About Us; Faq; For Patients . Colon Cancer; ... PalloR; Additional symptoms of pheochromocytoma diagnosis: Constipation; Tremor; Weight loss ...These "spells" are often accompanied by symptoms of cold peripheries and facial pallor. These symptoms have repercussions for patients' daily lives and could render patients more vulnerable to experiencing unique psychosocial stressors. Second, catecholamine disruption may cause deficits in the medial frontal cortical regions and amygdala.Hereditary Paraganglioma-Pheochromocytoma Syndrome via the SDHAF2 Gene. GTR Test ID Help Each Test is a specific, orderable test from a particular laboratory, and is assigned a unique GTR accession number. The format is GTR00000001.1, with a leading prefix 'GTR' followed by 8 digits, a period, then 1 or more digits representing the version. ...Paroxysmal symptoms which suggest seizure disorder, anxiety attacks or hyperventilation. Occurs in half of patients; Usually sudden in onset but variable in length (eg min-several hr) Associated w/ headache, sweating, palpitations, apprehension, chest or abdomen pain, N/V; Pallor may occur; Very high BP usually w/ tachycardia; Other SymptomsKeep reading to understand what it is to be a 'zebra' WARNING - MEDICAL JARGON OVERLOAD 🤓 Pheochromocytoma is an extremely rare tumor, ordinarily benign, which is situated on one or both of the adrenal glands. ... pallor; symptoms can vary depending on the individual - less or more; Some people may also find they can go days without an ...Pheochromocytoma causes high blood pressure, and left untreated, can result in severe or life-threatening damage to other body systems, especially the cardiovascular system. Other symptoms include: Heavy sweating Headache Rapid heartbeat (tachycardia) Tremors Paleness in the face (pallor) Shortness of breath (dyspnea) Diagnosis56-yr-old male with pheochromocytoma and ischemic enterocolitis n/a 8.5× 5× 7 n/a Survived 65-yr-old female with pheochromocytoma and ischemic enterocolitis 135 8.5 in greatest diameter 22,922 (135,000) Survived 26-yr-old female with pheochromocytoma and gross dilatation of the colon 1440 hemorrhagic n/a n/a DiedCombinations of symptoms can be of value: 2 or more symptoms from the triad of headache, palpitations, and diaphoresis were present in the majority of pheochromocytoma patients, but in a smaller number of non-pheochromocytoma patients. The presence of the entire triad is more specific, but less sensitive.Other Typical Signs and Symptoms of Pheochrmocytoma Include: Headaches (severe) Excess sweating (generalized) Racing heart (tachycardia and palpitations) Anxiety and nervousness Nervous shaking (tremors) Pain in the lower chest or upper abdomen Nausea (with or without vomiting) Weight loss Heat intolerance Weight loss Recent onset of hypertensionThus, patients with EPI-secreting pheochromocytomas more frequently show episodic symptoms and signs with palpitations, light-headedness or syncope, anxiety, and hyperglycemia than patients with tumors that secrete mainly NE, who more often have continuous symptoms and signs including hypertension, sweating, and headache ( 3, 17, 19 ).Other symptoms that may occur during a pheochromocytoma spell include: Tremor Nausea Weakness Anxiety / panic attacks Stomach pain Side pain Constipation Dizziness on standing caused by low blood pressure Retinal damage due to high blood pressure Weight loss Paleness (pallor) Fever Tremor Neurofibromas Fast, irregular heartbeatsPheochromocytoma is a rare tumor that usually starts in the cells of one of your adrenal glands. Although they are usually benign, pheochromocytomas often cause the adrenal gland to make too many hormones. This can lead to high blood pressure and cause symptoms such as . Headaches; Sweating; Pounding of the heart; Being shaky; Being extremely paleWith the growth of tumour, the symptoms also increase in frequency and severity. Abdominal pain, chest pain, irritability, nervousness, pallor, palpitations, rapid heart rate, severe headache, sweating, weight loss, hand tremor, high blood pressure and sleeping difficulty are some of the most common symptoms of pheochromocytoma.With the growth of tumour, the symptoms also increase in frequency and severity. Abdominal pain, chest pain, irritability, nervousness, pallor, palpitations, rapid heart rate, severe headache, sweating, weight loss, hand tremor, high blood pressure and sleeping difficulty are some of the most common symptoms of pheochromocytoma.These may be variable but typically include palpitation, tremor, diaphoresis, and headache. Attacks may start as a feeling of shortness of breath followed by chest pain and headache. Coldness in the hands and feet and facial pallor may occur. Spells may occur multiple times daily or as infrequently as once monthly.A pheochromocytoma-induced hypertensive crisis may precipitate hypertensive encephalopathy, which is characterized by altered mental status, focal neurologic signs and symptoms, or seizures. Other neurologic complications include stroke from cerebral infarction or an embolic event secondary to a mural thrombus from dilated cardiomyopathy.The clinical presentation of pheochromocytoma can vary greatly, but hypertension, tachycardia, pallor, headache and feelings of panic or anxiety are typically evident. 3,4,6 The signs and symptoms ...Summary Obstructive sleep apnea (OSA) is a condition of intermittent nocturnal upper airway obstruction. OSA increases sympathetic drive which may result in clinical and biochemical features suggestive of pheochromocytoma. We present the case of a 65-year-old male with a 2.9-cm left adrenal incidentaloma on CT, hypertension, symptoms of headache, anxiety and diaphoresis, and persistently ...again, it is important to ask the patient about their present and past history of sympathetic autonomic symptoms (palpitation, perspiration, pallor, tremor, or anxiety) and neck surgery. 4.6 intracranial pheochromocytoma brain metastases of pheochromocytoma are extr emely rare, and intracranial lesions are the only sites of metastasis in patients …8. Why would a patient with a pheochromocytoma sweat excessively, have facial pallor, and be constipated? Patients that have pheochromocytomas sweat excessively, have facial pallor and can be constipated because the tumor is located in the adrenal gland where hormones are secreted. When hormones are off balance it can cause symptoms such as these.Pheo can be however asymptomatic. The classical triad of symptoms consists of palpitations, headaches and profuse sweating. Other symptoms include: anxiety, pallor, nausea, weakness. Case Presentation A 60 -year- old man was admitted to the hospital, because of a left adrenal tumor incidentally found during abdominal ultrasound (US).Other possible symptoms include: Anxiety attacks Fever Irregular heartbeat Extreme paleness in the face Shortness of breath Tremors or shakiness Nausea Vomiting Clammy skin Constipation Tingling fingers Vision disturbances Chest or stomach pain Weight loss High blood sugar levels Symptom triggersThe most common ages for symptoms of a disease to begin is called age of onset. Age of onset can vary for different diseases and may be used by a doctor to determine the diagnosis. For some diseases, symptoms may begin in a single age range or several age ranges. For other diseases, symptoms may begin any time during a person's life.The clinical presentation of pheochromocytoma can vary greatly, but hypertension, tachycardia, pallor, headache and feelings of panic or anxiety are typically evident. 3,4,6 The signs and symptoms ...Pheo can be however asymptomatic. The classical triad of symptoms consists of palpitations, headaches and profuse sweating. Other symptoms include: anxiety, pallor, nausea, weakness. Case Presentation A 60 -year- old man was admitted to the hospital, because of a left adrenal tumor incidentally found during abdominal ultrasound (US).The release of excessive catecholamines results in high blood pressure and other characteristic symptoms of pheochromocytoma. Additional symptoms that occur less frequently may include pain in the chest or abdomen, nausea, vomiting, diarrhea, constipation, pale skin (pallor), weakness and weight loss.Pheochromocytoma and Congestive Heart Failure. Science topic Pheochromocytoma. ... there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and ... Pheochromocytoma (PCC) is a rare catecholamine-secreting neoplasm of adrenal origin; when it is extra-adrenal, it is referred to as paraganglioma. PCC is known as the "great masquerader" because of its similarity in clinical presentation to many other conditions. ... severe headache, tremors, pallor, and dyspnea. Atypical symptoms include ...These “spells” are often accompanied by symptoms of cold peripheries and facial pallor. These symptoms have repercussions for patients’ daily lives and could render patients more vulnerable to experiencing unique psychosocial stressors. Second, catecholamine disruption may cause deficits in the medial frontal cortical regions and amygdala. tachycardic, and have palpitations. 1,2 Other symptoms include a forceful heartbeat, facial pallor, cold hands and feet, and tremor, which are caused by the peripheral vasoconstriction. Some patients describe the episode as starting with a sudden "rush" in the chest, shortness of breath, followed by a forceful heartbeat and throbbing headache.Symptoms: [ Waguespack, 2010 ] Headache, Palpitations, Diaphoresis = "Classic" triad Hypertension Often sustained, rather than episodic Can cause Hypertensive Crisis Syncope Pallor Anxiety! End Organ Injury Cardiomyopathy CVA Pancreatitis Death (the ultimate end organ damage) Symptoms from ectopic hormone production Gigantism Cushing syndrome SIADHSymptoms and signs of pheochromocytoma include the following: Headache Diaphoresis Palpitations Tremor Nausea Weakness Pallor Anxiety, sense of doom Epigastric pain Flank pain Constipation ...Presents with palpitations, diaphoresis, pallor, and paroxysmal hypertension. Risk factors include multiple endocrine neoplasia type 2, Von Hippel-Lindau syndrome, and neurofibromatosis type 1. Diagnosed by increased levels of urine and serum catecholamines, metanephrines, and normetanephrines. T...The release of excessive catecholamines results in high blood pressure and other characteristic symptoms of pheochromocytoma. Additional symptoms that occur less frequently may include pain in the chest or abdomen, nausea, vomiting, diarrhea, constipation, pale skin (pallor), weakness and weight loss.Answer (1 of 4): When can symptoms of a pheochromocytoma occur? Pheochromocytomas may occur in persons of any age, but the peak incidence is from the third to the fifth decades of life. Approximately 10% occur in children. History Symptoms and signs of pheochromocytoma include the following: ...Headache with Pheochromocytoma & Pallor Symptom Checker: Possible causes include Pheochromocytoma. Check the full list of possible causes and conditions now! ... Symptoms of pheochromocytoma in pregnancy Cases (%) Hypertension 90 Headaches 70 Palpitations 40 Sweating 35 Anxiety 30 Blurred vision 20 Convulsions 10 Dyspnea 10 * Adapted [glowm.com]Jan 25, 2021 · What Are Symptoms of Paragangliomas and Pheochromocytomas? The adrenal glands produce hormones called catecholamines, such as adrenaline (epinephrine) and noradrenaline ( norepinephrine ). These catecholamines help control heart rate, blood pressure , blood sugar , and the way the body reacts to stress . A patient with pheochromocytoma can have symptoms such as exsessive sweating, facial pallor, and constipation due to the tumors location in the adrenal gland where hormones are being secreted off balance. This off balance of hormones that are secreted contribute to these symptoms in the patient. Describe the methods used to diagnose a ...Dec 01, 2016 · Pheochromocytoma causes a variety of signs and symptoms, including (in alphabetical order): Abdominal pain; Constipation; Chest pain; Dizziness; Elevated blood sugar; Facial flushing (redness) High blood pressure; Increased respiratory rate; Nausea; Nervousness, anxiety, and irritability; Pale skin tone; Rapid heart rate and heart palpitations; Severe headaches; Sweating Unfortunately, people suffering from cancerous pheochromocytoma have a 5-year survival rate of only 50%. Pheochromocytoma is a rare but deadly condition which is why it is of utmost importance to seek medical advice if you have symptoms of this disease. Source: J. Alastair, I. and Simon, M., 2016. A pheochromocytoma is an endocrine tumor located in the adrenal glands that releases abnormal amounts of catecholamine hormones. This type of tumor arises from chromaffin cells (also called pheochromocytes) present in the adrenal medulla. The adrenal medulla is located in the center of the adrenal glands (also known as suprarenal glands) and ...During this procedure, MIBG, a compound containing a small amount of radioactivity, is injected into a vein and is picked up by pheochromocytoma cells, but not normal cells. 1 The body is scanned with a scanner that detects the MIBG. Any MIBG that is seen with the scanner can indicate the presence of pheochromocytoma cells.The release of excessive catecholamines results in high blood pressure and other characteristic symptoms of pheochromocytoma. Additional symptoms that occur less frequently may include pain in the chest or abdomen, nausea, vomiting, diarrhea, constipation, pale skin (pallor), weakness and weight loss.Pallor/weight loss; Parasympathetic nervous system tumors Usually in head and neck region, or aortic root; Tumors are usually nonsecreting; Symptoms are due to compression or infiltration of adjacent structures (including cranial nerves) Pediatrics Epidemiology. Incidence - rare, but the most common pediatric endocrine tumorSymptoms: [ Waguespack, 2010 ] Headache, Palpitations, Diaphoresis = "Classic" triad Hypertension Often sustained, rather than episodic Can cause Hypertensive Crisis Syncope Pallor Anxiety! End Organ Injury Cardiomyopathy CVA Pancreatitis Death (the ultimate end organ damage) Symptoms from ectopic hormone production Gigantism Cushing syndrome SIADHPharmacologically, epinephrine is known to raise the systolic blood pressure and pulse rate. Elevation of the blood sugar, hypermeta bolism, apprehension, mydriasis, and other phenomena are also produced. Norepine phrine increases both systolic and diastolic blood pressure, slows the pulse, and has far less effect on the other body processes.56-yr-old male with pheochromocytoma and ischemic enterocolitis n/a 8.5× 5× 7 n/a Survived 65-yr-old female with pheochromocytoma and ischemic enterocolitis 135 8.5 in greatest diameter 22,922 (135,000) Survived 26-yr-old female with pheochromocytoma and gross dilatation of the colon 1440 hemorrhagic n/a n/a DiedAlthough nausea and vomiting is observed with preeclampsia, abdominal pain, often over the liver, is also present in preeclampsia but not with pheochromocytoma. Other notable symptoms described in the literature include nervousness, pallor, fever, and cardiovascular manifestations, such as arrhythmias, angina pectoris, dilated cardiomyopathy ...Pheochromocytoma is a rare and mostly benign tumor that secretes the Catecholamines Nor Epinephrine and Epinephrine. The release of these hormones causes deadly hypertension with blood pressures over 250 mm/hg and a fight or flight reaction with symptoms including; skin flush, pallor, sweating, anxiety, palpitations and elevated heart rate ...Other Typical Signs and Symptoms of Pheochrmocytoma Include: Headaches (severe) Excess sweating (generalized) Racing heart (tachycardia and palpitations) Anxiety and nervousness Nervous shaking (tremors) Pain in the lower chest or upper abdomen Nausea (with or without vomiting) Weight loss Heat intolerance Weight loss Recent onset of hypertensionSystemically, the main clinical feature is hypertension, although pheochromocytomas are present in only about 0.2% of those with high blood pressure. Increased blood pressure may be an abrupt, precipitous elevation associated with tachycardia, palpitations, headache, sweating, tremor, postural hypotension, fever, pallor and weight loss.Unfortunately, people suffering from cancerous pheochromocytoma have a 5-year survival rate of only 50%. Pheochromocytoma is a rare but deadly condition which is why it is of utmost importance to seek medical advice if you have symptoms of this disease. Source: J. Alastair, I. and Simon, M., 2016. The classic triad of symptoms associated with pheochromocytoma includes episodic headache (90%), sweating (60-70%), and palpitations (70%). 2,5 Sustained or paroxysmal hypertension is the most common symptom reported in about 95% of patients with pheochromocytoma. Other symptoms include pallor, tremors, dyspnea, generalized weakness ...Symptoms and signs of pheochromocytoma include the following: Headache Diaphoresis Palpitations Tremor Nausea Weakness Pallor Anxiety, sense of doom Epigastric pain Flank pain Constipation ...Other symptoms that may occur during a pheochromocytoma spell include: Tremor Nausea Weakness Anxiety / panic attacks Stomach pain Side pain Constipation Dizziness on standing caused by low blood pressure Retinal damage due to high blood pressure Weight loss Paleness (pallor) Fever Tremor Neurofibromas Fast, irregular heartbeatsThe symptoms and signs of pheochromocytoma ( Table I) are mainly due to hypercatecholaminemia and hypertension. Headaches occur in any part of the head; they may be mild but are usually severe and throbbing (especially during paroxysmal hypertension) and are often accompanied by nausea and vomiting.Unfortunately, people suffering from cancerous pheochromocytoma have a 5-year survival rate of only 50%. Pheochromocytoma is a rare but deadly condition which is why it is of utmost importance to seek medical advice if you have symptoms of this disease. Source: J. Alastair, I. and Simon, M., 2016. Other common symptoms are severe anxiety, fatigue, weakness, tremulousness, nausea, dyspnea, weight loss despite normal appetite (which is a result of catecholamine-induced breakdown of sugar and ...Pheochromocytomas, which arise from the adrenal medulla, typically lead to catecholamine excess. Symptoms of PGL/PCC result from either mass effects or catecholamine hypersecretion (e.g., sustained or paroxysmal elevations in blood pressure, headache, episodic profuse sweating, forceful palpitations, pallor, and apprehension or anxiety).Pheochromocytoma is a rare tumor of adrenal gland tissue. It results in the release of too much epinephrine and norepinephrine, hormones that control heart rate, metabolism, and blood pressure. Endocrine glands release hormones (chemical messengers) into the bloodstream to be transported to various organs and tissues throughout the body. For ...A pheochromocytoma is a type of tumor found in the adrenal glands or certain nerve cells. These tumors are very rare but can cause dramatic symptoms because they tend to secrete large amounts of certain hormones called catecholamines.Though some pheochromocytomas can arise in nerve cells, almost all of them tend to be found in one of the two adrenal glands.Classical symptoms are spell-like and caused by catecholamine surges, which cause episodic palpitations, headache, pallor, perspiration and anxiety. Signs are tachycardia, hypertension.Pheochromocytoma causes high blood pressure, and left untreated, can result in severe or life-threatening damage to other body systems, especially the cardiovascular system. Other symptoms include: Heavy sweating Headache Rapid heartbeat (tachycardia) Tremors Paleness in the face (pallor) Shortness of breath (dyspnea) DiagnosisApart from the above classic presentation, pheo - chromocytoma can also present with nonspecific symptoms such as flushing, nausea, tiredness or weight loss. Abdominal pain and constipation or chest pain mimicking myocardial infarction as in the case of inverted takotsubo cardiomyopathy can be caused by sudden catecholamine releaseThus, patients with EPI-secreting pheochromocytomas more frequently show episodic symptoms and signs with palpitations, light-headedness or syncope, anxiety, and hyperglycemia than patients with tumors that secrete mainly NE, who more often have continuous symptoms and signs including hypertension, sweating, and headache ( 3, 17, 19 ). 10l_1ttl